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doi: 10.1073/pnas.2112561118 151 MisilimuD.LiW.ChenD.WeiP.HuangY.LiS.et al

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Research conducted in vivo and in vitro has shown that acrolein causes oxidative stress, resulting in the rupture of cell membranes, DNA and mitochondria damage, endoplasmic reticulum (ER) stress, and the potential to initiate apoptosis (112, 113)